Raum:
ND 04/589a
Tel:
+49 (0)234 32-25548
Email: Carolin.muegge@rub.de
orcid.org/0000-0002-8065-173X
Welcome to my research group committed to sustainable production solutions
Advancing Sustainable Production
My primary research focus lies in uncovering solutions for sustainable production processes. Often, a compound holds potential in various industrial contexts, ranging from pharmaceuticals to fine or bulk chemicals. However, harnessing its benefits is far from environmentally friendly. This prompts the vital question: "How can we generate this compound in a manner that is both economically efficient and environmentally conscious?" The answer isn't a singular solution; it involves exploring numerous avenues and methodologies.
The power of biotechnology
This is where biotechnology comes into play—an ideal launching point. Using enzymes as natural catalysts, we can drive reactions that might remain inaccessible via traditional chemical approaches. When these biocatalytic reactions interweave with other potent techniques, the result is a cascade effect, carrying immense potential for industrial applications.
Renewable resources and unconventional pathways
Within this framework, my research delves into producing bulk chemicals sourced from renewable resources. This may be achieved through whole-cell biocatalysis, involving the orchestration of multiple enzymes within a single cellular environment, or via finely tuned enzyme formulations. My team and I also explore the integration of biocatalysis with chemo- or electrocatalysis, unveiling more pathways for innovation. Additionally, my curiosity extends to the renewal of nicotinamide cofactors—integral to countless enzymatic redox reactions—significantly impacting cost-efficiency and efficacy in biotechnological applications.
Join Me on This Journey
Whether you're a fellow student eager for insights or a collaborator with shared interests, I invite you to embark on this research expedition alongside me. Together, we can unravel groundbreaking solutions that harmonize sustainable practices with cutting-edge science.
Feel free to explore my work and reach out—let's pioneer the future of sustainable production together!
Homepage: https://reco2nwert.de/
Press releases: intern, extern
Viele industrielle Prozessgase enthalten CO2, das in die Atmosphäre freigesetzt wird und langfristig unser Klima beeinflusst. Die Nutzung von CO2 als Rohstoff für biotechnologische Produktionsprozesse trägt daher maßgeblich zur Reduktion von CO2-Emissionen bei. In diesem Zusammenhang zielt ReCO2NWert darauf ab, unvermeidbare Prozessgase biotechnologisch zur Kohlenstofffixierung in industriell nutzbare Endprodukte umzuwandeln. Dies trägt zur Transformation der fossilbasierten chemischen Industrie im und um das rheinische Revier hin zu einer biobasierten und nachhaltigeren Industrie bei.
Im Projekt werden die gereinigten Abgase aus der MVA Weisweiler gesammelt und mit Hilfe von Mikroorganismen in industriell relevante Produkte umgewandelt. Die Mikroorganismen können CO2 und ähnliche C1-Gase aufnehmen und in wertvolle Produkte umwandeln. Dazu gehören beispielsweise Alkohole, die in der chemischen Industrie zur Herstellung von Kunststoffen oder Inhaltsstoffen für Kosmetikprodukte verwendet werden. Das Projekt strebt an, eine biotechnologische Plattformtechnologie zur Nutzung kohlenstoffreicher Industriegase zu etablieren, die in Zukunft für verschiedene Abgasströme und Produkte eingesetzt werden kann.
Unser Team konzentriert sich auf die enzymatische Aufwertung von Zwischenprodukten, die aus der C1-Fixierung gewonnen werden. Wir erforschen verschiedene enzymatische Klassen und Biotransformationsformate, um Produkte herzustellen, die für verschiedene Industriepartner wertvoll sind.
ReCO2NWert wird vom BMFTR im Rahmen des Strukturwandelprogramms gefördert (FKZ: 031B1503G).
Carolin Mügge obtained diploma degree in Chemistry at Friedrich-Schiller-Universität Jena in 2009. She embarked on her doctoral research at the same university, successfully completing her dissertation on "Metal Complexes with Sulfur Ligands as Cytotoxic Agents" in 2015. Throughout her studies and doctoral program, she received scholarships from the Studienstiftung des deutschen Volkes and the Carl-Zeiss-Stiftung.
Following her doctoral degree, Carolin Mügge became postdoctoral researcher in the Microbial Biotechnology team (Jun.-Prof. Dr. R. Kourist) at RUB. She then took charge of the Junior Research Group ChemBioCat / Microbial Biotechnology in 2017. Currently, she serves as a scientific group leader in the Microbial Biotechnology research group headed by Dirk Tischler.
Carolin Mügge has participated in various professional development activities and research stays. She served as a guest researcher at University of Florence multiple times and also at Ruhr-Universität Bochum during her doctoral studies. She is a member of professional societies including DECHEMA Gesellschaft für Chemische Technik und Biotechnologie e.V., Vereinigung für Allgemeine und Angewandte Mikrobiologie e.V. (VAAM), Gesellschaft Deutscher Chemiker (GDCh), and Deutsche Gesellschaft für Fettwissenschaften (DGF).
She actively engages in various committees and commissions at Ruhr-Universität Bochum, including the Equal Opportunity Commission and the University Commission for Diversity, Inclusion, and Talent Development. She is also a member of the Early Career Research Board at RUB Research School and the Faculty Council of the Faculty of Biology and Biochemistry. She contributes as a referee for journals with peer-review processes, including Frontiers in Microbiology, J. Biotechnology, Process Biochemistry, and MDPI Journals.